Brief communication
Thrombospondin-1 serum levels do not correlate with pelvic pain in patients with ovarian endometriosis
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* Corresponding author: Manuel G Manero mgmanero@unav.es
1 Department of Obstetrics and Gynecology, Clínica Universitaria de Navarra, University of Navarra, Pamplona, Spain
2 Department of Obstetrics and Gynecology, Hospital San Jorge, Huesca, Spain
Journal of Ovarian Research 2009, 2:18 doi:10.1186/1757-2215-2-18
Published: 16 November 2009Abstract
Objetive
Thrombospondin-1 serum levels is correlate with pelvic pain in patients with ovarian endometriosis.
Patients
Thrombospondin-1 serum levels were prospectively analysed in 51 patients (group A asymptomatic patients or patients presenting mild dysmenorrhea and women comprised group B severe dysmenorrhea and/or chronic pelvic pain and/or dyspareunia) who underwent surgery for cystic ovarian endometriosis to asses whether a correlation exists among thrombospondin-1 serum levels and pelvic pain.
Results
From 56 patients, five cases were ultimateley excluded, because the histological diagnosis was other than cystic ovarian endometriosis (2 teratomas and 3 haemorragic cysts). The mean thrombospondin-1 serum levels in group A was 256,69 pg/ml_+37,07 and in group B was 291,41 pg/ml + 35,59.
Conclusion
Pain symptoms in ovarian endometriosis is not correlated with thrombospondin-1 serum levels.