Brief communication

Thrombospondin-1 serum levels do not correlate with pelvic pain in patients with ovarian endometriosis

Manuel García Manero¹ , Begoña Olartecoechea¹ , Pedro Royo² and Juan Luis Alcázar¹

¹  Department of Obstetrics and Gynecology, Clínica Universitaria de Navarra, University of Navarra, Pamplona, Spain

²  Department of Obstetrics and Gynecology, Hospital San Jorge, Huesca, Spain

author email corresponding author email

Journal of Ovarian Research 2009, 2:18doi:10.1186/1757-2215-2-18

Published:	16 November 2009

Abstract

Objetive

Thrombospondin-1 serum levels is correlate with pelvic pain in patients with ovarian endometriosis.

Patients

Thrombospondin-1 serum levels were prospectively analysed in 51 patients (group A asymptomatic patients or patients presenting mild dysmenorrhea and women comprised group B severe dysmenorrhea and/or chronic pelvic pain and/or dyspareunia) who underwent surgery for cystic ovarian endometriosis to asses whether a correlation exists among thrombospondin-1 serum levels and pelvic pain.

Results

From 56 patients, five cases were ultimateley excluded, because the histological diagnosis was other than cystic ovarian endometriosis (2 teratomas and 3 haemorragic cysts). The mean thrombospondin-1 serum levels in group A was 256,69 pg/ml_+37,07 and in group B was 291,41 pg/ml + 35,59.

Conclusion

Pain symptoms in ovarian endometriosis is not correlated with thrombospondin-1 serum levels.