Table 4 |
|||||
|
GPX3 associations with cancer |
|||||
|
Cancer Type |
Overexpression/ Downregulation |
RNA/ Protein |
Cell/Tissue/ Serum/Plasma |
Species |
References |
|
|
|||||
|
Esophageal Squamous Cell |
Downregulation |
mRNA, protein |
Tumor tissue |
Human |
[31] |
|
Gastric, Cervical, Thyroid, Head, Neck, Lung and Melanoma |
Downregulation |
mRNA, protein |
Tumor tissue |
Human |
[32] |
|
Thyroid |
Downregulation |
mRNA |
Tumor tissue |
Human |
[33] |
|
Ovarian Clear Cell |
Upregulation |
mRNA |
Cell Lines |
Human |
[25] |
|
Ovarian Clear Cell |
Upregulation |
mRNA, protein |
Tumor tissue |
Human |
[24] |
|
Ovarian Clear Cell |
Upregulation |
mRNA |
Tumor tissue |
Human |
[26] |
|
Ovarian Papillary Serous: Late Stage/previously treated |
Presence |
Protein |
Ascites Fluid |
Human |
[27] |
|
Glioblastoma |
Downregulation |
mRNA, protein |
Tumor tissue, Serum |
Human |
[20] |
|
Meningioma |
Downregulation |
mRNA |
Tumor Tissue |
Human |
[34] |
|
Lung |
Downregulation |
protein |
Whole blood, Plasma (activity measurement) |
Human |
[35] |
|
Endometrial adenocarcinoma |
Downregulation |
mRNA |
Tumor Tissue |
Human, Rat |
[19] |
|
Barrett's adenocarcinoma |
Downregulation |
mRNA |
Tumor Tissue |
Human |
[36] |
|
Prostate |
Downregulation |
mRNA |
Tumor tissue |
Human |
[23] |
|
Lung |
Upregulation |
protein |
Blood serum |
Mouse |
[37] |
|
Prostate cancer |
Upregulation |
protein |
Blood serum |
Human, Rat |
[38] |
|
|
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|
Agnani et al. Journal of Ovarian Research 2011 4:18 doi:10.1186/1757-2215-4-18 |
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