Journal of Ovarian Research

unofficial impact factor 2.10

Open Access Research

Suppression of cancer stemness p21-regulating mRNA and microRNA signatures in recurrent ovarian cancer patient samples

Michael F Gallagher1,2*, Cynthia CBB Heffron1,4, Alexandros Laios1,3, Sharon A O'Toole1,3, Brendan Ffrench1,2, Paul C Smyth1, Richard J Flavin2, Salah A Elbaruni1,2, Cathy D Spillane1,2, Cara M Martin1,2, Orla M Sheils1,2 and John J O'Leary1,2

Author Affiliations

1 Department of Histopathology, University of Dublin, Trinity College. Trinity Centre for Health Sciences, St James' Hospital, Dublin 8, Ireland

2 Molecular Pathology Research Laboratory, Coombe Women's and Infants' University Hospital, Dublin 8, Ireland

3 The Department of Obstetrics and Gynecology, Trinity Centre for Health Sciences, St James' Hospital, Dublin 8, Ireland

4 The Department of Histopathology, Cork University Hospital, Wilton, Cork, Ireland

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Journal of Ovarian Research 2012, 5:2 doi:10.1186/1757-2215-5-2

Published: 19 January 2012

Additional files

Additional file 1:

Microarray and functional relationship analysis of early differentiation response of SCC-PSA1 cells. This file contains genelists of genes upregulated and downregulated by SCC-PSA1 cells in response to differentiation stimulus. This file also contains results of analysis to identify functional relationships between these genes.

Format: XLS Size: 114KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 2:

Microarray and functional relationship analysis of early differentiation response of NULLI-SCC cells. This file contains genelists of genes upregulated and downregulated by NULLI-SCC cells in response to differentiation stimulus. This file also contains results of analysis to identify functional relationships between these genes.

Format: XLS Size: 56KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 3:

Microarray and functional relationship analysis of early differentiation response of mES cells. This file contains genelists of genes upregulated and downregulated by mES cells in response to differentiation stimulus. This file also contains results of analysis to identify functional relationships between these genes.

Format: XLS Size: 195KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 4:

Microarray and functional relationship analysis of primary versus recurrent tumor samples. This file contains genelists of genes upregulated and downregulated in primary versus recurrent tumor samples. This file also contains results of analysis to identify functional relationships between these genes.

Format: XLS Size: 234KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 5:

Comparison of microRNA expression in hEC and primary versus recurrent tumor samples. This file details the relative expression patterns and levels of microRNAs in hEC cells and primary versus recurrent tumor samples and the pathway associations of genes targeted by these microRNAs.

Format: XLS Size: 41KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data