Open Access Case report

Massive edema of ovary with cytogenetic alteration of chromosome 12q13-15 in adolescent patient: a case report

Rossella De Cecio1, Monica Cantile12*, Nicola Fortunato1, Annarosaria De Chiara1, Nunzia Simona Losito1, Renato Franco1 and Gerardo Botti1

Author Affiliations

1 Pathology Unit, Istituto Nazionale Tumori Fondazione “G. Pascale”, via Mariano Semmola, 80131, Napoli, Italy

2 Pathology Unit, National Cancer Institute, Pascale Hospital, via Mariano Semmola, 80131, Naples, Italy

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Journal of Ovarian Research 2013, 6:13  doi:10.1186/1757-2215-6-13

Published: 7 February 2013



The massive edema of ovary, with or without fibromatosis, is a rare tumor-like entity characterized by an increase in volume of one or both ovaries for accumulation of edema fluid in the stroma that separates the follicular structures.


We report a rare case, very peculiar also for its association with a massive stromal fibromatosis and for the presence, never described, of tumoral areas with CHOP gene translocation, on chromosome 12q13–15.

Ovarian edema; Sarcoma-like; CHOP translocation